RMR2

Project Overview

The aim of the RMR project pipeline is an ambitious one: to identify a longevity intervention or treatment program which doubles the remaining lifespan of wild-type adult mice. While the landscape of longevity interventions continues to balloon, nearly all therapies zero in on addressing a single aging hallmark. At LEV Foundation, we believe robust rejuvenation will require targeting multiple aging hallmarks simultaneously, and additionally, that now is the time to begin this approach, a strategy largely underemployed by the research and startup communities.

While the RMR program aims to achieve robust rejuvenation in rodents, the implications of a successful outcome reach far beyond laboratory animals. Demonstrable rejuvenation in aged wild-type animals is a key step in securing broad public support of rejuvenation medicine extending beyond ‘soft’ targets such as lifestyle and supplementation, as well as for convincing policymakers.